[Products Name]                Pueraria

[Molecular Formula]          C15H12O

[CAS No.]                             3681-99-0

[Product Description]    
Naringenin is a potent inhibitor of the cytochrome p450 liver enzymes: CYP1A2, CYP3A3 and CYP3A4. There is however, considerable inter-individual variability in the effects of grapefruit juice on drug metabolism, in part due to
1） amount of naringenin formed by an individual,
2） amount of naringin present in a brand of grapefruit juice,
3） dilution of grapefruit juice used, and 4） other substances in grapefruit juice accounting for the interactioResearchers at the University of Western Ontario                         in London discovered, while using various juices to hide the taste of a test substance given to patients along with their drugs as part of a cancer                                            trial, that there was a synergistic or more effective action of the drug to breast cancer when it was given with Grapefruit Juice.

Human breast cancer cells in test tubes that were estrogen-insensitive;that is, the cells did not need estrogen to cock and prime them into maligency, respond well      to a flavonoid found in grape juice, naringenin. Naringenin proved almost   8 times more potent at halting breast cancer cells's gro wth than another flavonoid,       genestein from soy beans.